The Role of Meningeal Populations of Type II Innate Lymphoid Cells in Modulating Neuroinflammation in Neurodegenerative Diseases

Scientists review the current evidence of type II innate lymphoid cells (ILC2)-mediated modulation of neuroinflammatory cues within the central nervous system (CNS), highlight the distribution of ILC2s in both the periphery and CNS, and discuss some challenges associated with cell type-specific targeting that are important for therapeutics.