[Nature Communications] Scientists found that MARCH2 expression is significantly reduced in cardiac macrophages from doxorubicin-induced cardiomyopathy (DiCM) mice and human dilated cardiomyopathy patients.
[Advanced Healthcare Materials] The authors investigated the role of surface charge and synergistic mechano-electrical stimulation of piezoelectric poly(vinylidene fluoride) on the behaviour of H9c2 cardiac cells.
[British Journal of Cancer] Researchers investigated the role of the ALOX5 metabolism axis in doxorubicin-induced cardiomyopathy and to elucidate its underlying mechanism using genetic and pharmacological approaches.
[Cell Death & Disease] Scientists investigated the roles of DP427 and DP71 during cell proliferation and fibre differentiation. They included paralogous utrophins in our analyses, particularly the UP395 isoform, owing to its presence in muscle and its partial ability to compensate for the lack of DP427.
[Oncogene] Investigators showed that transforming growth factor β-activated kinase 1 (TAK1) expression and activity are markedly elevated in rhabdomyosarcoma cell lines and patient tumor specimens.
[Journal of Translational Medicine] Researchers revealed a novel m6A-mediated pathway that integrates biochemical (TGFβ1) and mechanical signals to direct skeletal muscle stem cells fate
[Nature] Using integrated single-cell, spatial, and functional analyses, scientists defined the earliest multicellular events that license this transition following oncogenic activation in the lung.
[Circulation] The functional role of SIRT5 in cardiac fibrosis was evaluated through cardiac fibroblast-specific knockout and overexpression of Sirt5 in mice.