Jamie Kang

[Journal of Ethnopharmacology] Investigators elucidated the potential mechanism of a traditional therapy for vitiligo and identified CASP7 and EP300 as potential key targets. Fufang Baizhi Tincture likely exerts its protective effects by modulating these targets to regulate melanocyte apoptosis and transcription, providing a robust scientific basis for its clinical application.

[Scientific Reports] Researchers examined the therapeutic potential of the neuropeptides neurotensin and substance P in reshaping inflammatory and microbial dynamics and accelerating wound closure in healthy and streptozotocin-induced diabetic mice models.

[Nature] Investigators characterized the genome and transcriptome of 123 acral melanoma tumours from 92 Mexican patients—a population notable because of its genetic admixture9.

[Proceedings of The National Academy of Sciences of The United States of America] The authors found that a specific protein, lamin B receptor (LBR), gets overproduced in aggressive melanoma.

[Journal of Nanobiotechnology] Researchers developed a biocompatible, ROS-responsive hydrogel platform for the local delivery of miR-665, which effectively attenuated inflammatory signaling and stimulated hair follicle regeneration in alopecia areata.

[Scientific Reports] Scientists used several pharmacological inhibitors to extend our understanding of Salinomycin-induced autophagy and its interactions with regulatory proteins, including the anticancer mechanism in cisplatin-resistant melanoma.