 | | Vol. 12.06 – 16 February, 2023 |
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| Investigators undertook single cell RNA sequencing and bioinformatic analyses to identify roles for different alveolar cell populations involved in mediating these retinoid-dependent responses.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers showed that basal cell differentiation correlated with a shift in cellular metabolism from glycolysis to fatty acid oxidation.
[Nature Communications] |
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| Scientists showed that expression of membrane-bound cytochrome B5 reductase 3 (CYB5R3), an enzyme critical for maintaining cellular redox homeostasis and soluble guanylate cyclase heme iron redox state, was diminished in idiopathic pulmonary fibrosis Type II alveolar epithelial cell.
[JCI Insight] |
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| Researchers reported that FAM13A was phosphorylated at the Serine 312 residue by AKT kinase after cigarette smoke extract treatment and thereby recognized by the CULLIN4A/DCAF1 E3 ligase complex, rendering the ubiquitination-mediated degradation of FAM13A.
[American Journal Of Physiology-Lung Cellular And Molecular Physiology] |
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| Scientists hypothesized that arginine to glycine at position 213 substituted extracellular superoxide dismutase variant protected against lung injury and inflammation via blockade of neutrophil-recruitment in an infectious model of methicillin-resistant S. aureus pneumonia.
[American Journal Of Physiology-Lung Cellular And Molecular Physiology] |
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| Conditioned media was collected and small extracellular vesicles were isolated from normal human bronchial epithelial cells and idiopathic pulmonary fibrosis-diseased human bronchial epithelial cells.
[Respiratory Research] |
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| Investigators isolated and evaluated the antineoplastic potential of grandivittin and its underlying mechanisms in human lung cancer A549 cells.
[Naunyn-Schmiedebergs Archives Of Pharmacology] |
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| Scientists examined the role and potential mechanism of long non-coding RNA PCAT6 in the development of lung adenocarcinoma.
[Molecular Biology Reports] |
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| Researchers studied the influence of DDX11-AS1 on paclitaxel resistance in lung adenocarcinoma.
[Pharmacogenomics] |
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| Investigators discuss the molecular biology underlying radiation-induced tumor immunity as well as pre-clinical and clinical studies combining radiation with immune checkpoint blockade treatments, with a focus on translational and clinical trials in small-cell lung cancer.
[Seminars In Cancer Biology] |
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| ENA Respiratory announced that INNA-051, a first-in-class, broad-spectrum, innate immunomodulator in development for the prophylaxis of respiratory viral infections, was found to significantly impact the course of viral infection in a Phase IIa flu challenge study.
[ENA Respiratory] |
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| February 21 – 23, 2023
London, England, United Kingdom |
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| | University of Louisville – Louisville, Kentucky, United States |
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| | Emory University – Atlanta, Georgia, United States |
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| | STEMCELL Technologies – Vancouver, British Columbia, Canada |
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| | IRCCS Candiolo Cancer Institute – Turin, Italy |
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| | Pompeu Fabra University – Barcelona, Spain |
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