Psoriatic Dermal-Derived Mesenchymal Stem Cells Induced C3 Expression in Keratinocytes

Investigators analyzed the C3 and its upstream S100A9, S100A8 and downstream MCP1 in psoriatic and control skin, and in normal human epidermal keratinocytes co-cultured with psoriatic versus control dermal-derived mesenchymal stem cells by mRNA, isobaric tags for relative and absolute quantitative, and simple Western analysis.