NewslettersIntestinal Cell NewsOrganoid NewsThe SMARCA4R1157WM Mutation Facilitates Chromatin Remodeling and Confers PRMT1/SMARCA4 Inhibitors Sensitivity in Colorectal CancerBy Laurisa Dohm - March 16, 20230135Researchers showed that the SMARCA4R1157WM mutant reinforced the transcriptional expression of EGFR and TNS4 to promote the proliferation of colorectal cancer cells and patient-derived tumor organoids.[NPJ Precision Oncology]Full Article