Ovol1/2 Loss-Induced Epidermal Defects Elicit Skin Immune Activation and Alter Global Metabolism

The authors demonstrated that inducible and simultaneous ablation of transcription factor-encoding Ovol1 and Ovol2 in adult epidermis results in barrier dysregulation through impacting epithelial-mesenchymal plasticity and inflammatory gene expression.
[EMBO Reports]
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