Twist Family BHLH Transcription Factor 1 Is Required for the Maintenance of Leukemia Stem Cell in MLL-AF9+ Acute Myeloid Leukemia

0
110
Scientists showed that TWIST1 was extremely highly expressed in the LSCs of MLL-AF9+ acute myeloid leukemia, and its upregulation was positively regulated by KDM4C in an H3K9me3 demethylation-dependent manner.
[Haematologica]
Abstract