Derived Myeloid Lineage Induced Pluripotent Stem as a Platform to Study Human CCR5Δ32 Homozygotes

Scientists developed a step-wise protocol that differentiated iPSCs from individuals homozygous for the C-C chemokine receptor type 5 (CCR5)Δ32 variant and healthy volunteers into myeloid lineage induced monocytes and macrophages.