Inhibition of the AURKA/YAP1 Axis Is a Promising Therapeutic Option for Overcoming Cetuximab Resistance in Colorectal Cancer Stem Cells

The authors used transcriptomic analysis along with in vitro and in vivo models of RAS/RAF wild-type CRC to study YAP1 Ser397 phosphorylation as a potential biomarker for cetuximab resistance.