Auranofin Repurposing for Lung and Pancreatic Cancer: Low CA12 Expression as a Marker of Sensitivity in Patient-Derived Organoids, with Potentiated Efficacy by AKT Inhibition

Our investigation employed a comprehensive drug screening of Auranofin in combination with eleven anticancer agents in cancerous PDAC and NSCLC patient-derived organoids, and non-cancerous pulmonary organoids.
[Journal Of Experimental & Clinical Cancer Research]
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