Blockade of TGF-β and PD-L1 by Bintrafusp Alfa Promotes Survival in Preclinical Ovarian Cancer Models by Promoting T Effector and NK Cell Responses

The authors tested whether coordinated blockade of TGF-β and PD-L1 with bintrafusp alfa could provoke anti-tumour immune responses in preclinical high-grade serous ovarian cancer models.