Extracellular Vesicles from Human iPSCs Enhance Reconstitution Capacity of Cord Blood-Derived Hematopoietic Stem and Progenitor Cells

By
Justin.choi
-
0
128
Scientists demonstrated that hiPSC-extracellular vesicles improved functional properties of cord blood-HSPCs critical for their hematopoietic capacity including metabolic, hematopoietic and clonogenic potential as well as survival, chemotactic response to stromal cell-derived factor 1 and adhesion to the model components of hematopoietic niche in vitro.
[Leukemia]
6445218 {6445218:KI5V9GA5} 1 apa 50 default 1 163645 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22KI5V9GA5%22%2C%22library%22%3A%7B%22id%22%3A6445218%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Karnas%20et%20al.%22%2C%22parsedDate%22%3A%222021-06-17%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BKarnas%2C%20E.%2C%20Seku%26%23x142%3Ba-Stryjewska%2C%20M.%2C%20Kmiotek-Wasylewska%2C%20K.%2C%20Bobis-Wozowicz%2C%20S.%2C%20Ryszawy%2C%20D.%2C%20Sarna%2C%20M.%2C%20Madeja%2C%20Z.%2C%20%26amp%3B%20Zuba-Surma%2C%20E.%20K.%20%282021%29.%20Extracellular%20vesicles%20from%20human%20iPSCs%20enhance%20reconstitution%20capacity%20of%20cord%20blood-derived%20hematopoietic%20stem%20and%20progenitor%20cells.%20%26lt%3Bi%26gt%3BLeukemia%26lt%3B%5C%2Fi%26gt%3B%2C%201%26%23x2013%3B14.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41375-021-01325-y%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41375-021-01325-y%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D6445218%26amp%3Bitem_key%3DKI5V9GA5%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Extracellular%20vesicles%20from%20human%20iPSCs%20enhance%20reconstitution%20capacity%20of%20cord%20blood-derived%20hematopoietic%20stem%20and%20progenitor%20cells%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22El%5Cu017cbieta%22%2C%22lastName%22%3A%22Karnas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ma%5Cu0142gorzata%22%2C%22lastName%22%3A%22Seku%5Cu0142a-Stryjewska%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katarzyna%22%2C%22lastName%22%3A%22Kmiotek-Wasylewska%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sylwia%22%2C%22lastName%22%3A%22Bobis-Wozowicz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Damian%22%2C%22lastName%22%3A%22Ryszawy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Micha%5Cu0142%22%2C%22lastName%22%3A%22Sarna%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Zbigniew%22%2C%22lastName%22%3A%22Madeja%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ewa%20K.%22%2C%22lastName%22%3A%22Zuba-Surma%22%7D%5D%2C%22abstractNote%22%3A%22%5Cu436f%5Cu7264%5Cu2062%5Cu6c6f%5Cu6f64%5Cu2028%5Cu4342%5Cu2920%5Cu7265%5Cu7072%5Cu6573%5Cu656e%5Cu7473%5Cu2061%5Cu2073%5Cu6f75%5Cu7263%5Cu6520%5Cu6f66%5Cu2068%5Cu656d%5Cu6174%5Cu6f70%5Cu6f69%5Cu6574%5Cu6963%5Cu2073%5Cu7465%5Cu6d20%5Cu616e%5Cu6420%5Cu7072%5Cu6f67%5Cu656e%5Cu6974%5Cu6f72%5Cu2063%5Cu656c%5Cu6c73%5Cu2028%5Cu4342%5Cu2d48%5Cu5350%5Cu4373%5Cu2920%5Cu666f%5Cu7220%5Cu626f%5Cu6e65%5Cu206d%5Cu6172%5Cu726f%5Cu7720%5Cu2842%5Cu4d29%5Cu2072%5Cu6563%5Cu6f6e%5Cu7374%5Cu6974%5Cu7574%5Cu696f%5Cu6e2c%5Cu2062%5Cu7574%5Cu2063%5Cu6c69%5Cu6e69%5Cu6361%5Cu6c20%5Cu4342%5Cu2061%5Cu7070%5Cu6c69%5Cu6361%5Cu7469%5Cu6f6e%5Cu2069%5Cu7320%5Cu6c69%5Cu6d69%5Cu7465%5Cu6420%5Cu696e%5Cu2061%5Cu6475%5Cu6c74%5Cu2070%5Cu6174%5Cu6965%5Cu6e74%5Cu7320%5Cu6475%5Cu6520%5Cu746f%5Cu2074%5Cu6865%5Cu2069%5Cu6e73%5Cu7566%5Cu6669%5Cu6369%5Cu656e%5Cu7420%5Cu6e75%5Cu6d62%5Cu6572%5Cu206f%5Cu6620%5Cu4342%5Cu2d48%5Cu5343%5Cu5043%5Cu7320%5Cu616e%5Cu6420%5Cu7468%5Cu6520%5Cu6c61%5Cu636b%5Cu206f%5Cu6620%5Cu6566%5Cu6665%5Cu6374%5Cu6976%5Cu6520%5Cu6578%5Cu2076%5Cu6976%5Cu6f20%5Cu6170%5Cu7072%5Cu6f61%5Cu6368%5Cu6573%5Cu2074%5Cu6f20%5Cu696e%5Cu6372%5Cu6561%5Cu7365%5Cu2043%5Cu422d%5Cu4853%5Cu5043%5Cu2066%5Cu756e%5Cu6374%5Cu696f%5Cu6e61%5Cu6c69%5Cu7479%5Cu2e20%5Cu5369%5Cu6e63%5Cu6520%5Cu6875%5Cu6d61%5Cu6e2d%5Cu696e%5Cu6475%5Cu6365%5Cu6420%5Cu706c%5Cu7572%5Cu6970%5Cu6f74%5Cu656e%5Cu7420%5Cu7374%5Cu656d%5Cu2063%5Cu656c%5Cu6c73%5Cu2028%5Cu6869%5Cu5053%5Cu4373%5Cu2920%5Cu6861%5Cu7665%5Cu2062%5Cu6565%5Cu6e20%5Cu696e%5Cu6469%5Cu6361%5Cu7465%5Cu6420%5Cu6173%5Cu2064%5Cu6f6e%5Cu6f72%5Cu2063%5Cu656c%5Cu6c73%5Cu2066%5Cu6f72%5Cu2062%5Cu696f%5Cu6163%5Cu7469%5Cu7665%5Cu2065%5Cu7874%5Cu7261%5Cu6365%5Cu6c6c%5Cu756c%5Cu6172%5Cu2076%5Cu6573%5Cu6963%5Cu6c65%5Cu7320%5Cu2845%5Cu5673%5Cu2920%5Cu6d6f%5Cu6475%5Cu6c61%5Cu7469%5Cu6e67%5Cu2070%5Cu726f%5Cu7065%5Cu7274%5Cu6965%5Cu7320%5Cu6f66%5Cu206f%5Cu7468%5Cu6572%5Cu2063%5Cu656c%5Cu6c73%5Cu2c20%5Cu7765%5Cu2061%5Cu7265%5Cu2074%5Cu6865%5Cu2066%5Cu6972%5Cu7374%5Cu2074%5Cu6f20%5Cu656d%5Cu706c%5Cu6f79%5Cu2068%5Cu6950%5Cu5343%5Cu2d64%5Cu6572%5Cu6976%5Cu6564%5Cu2045%5Cu5673%5Cu2028%5Cu6869%5Cu5053%5Cu432d%5Cu4556%5Cu7329%5Cu2074%5Cu6f20%5Cu656e%5Cu6861%5Cu6e63%5Cu6520%5Cu7468%5Cu6520%5Cu6865%5Cu6d61%5Cu746f%5Cu706f%5Cu6965%5Cu7469%5Cu6320%5Cu706f%5Cu7465%5Cu6e74%5Cu6961%5Cu6c20%5Cu6f66%5Cu2043%5Cu422d%5Cu6465%5Cu7269%5Cu7665%5Cu6420%5Cu4344%5Cu3435%5Cu6469%5Cu6d4c%5Cu696e%5Cu2d43%5Cu4433%5Cu342b%5Cu2063%5Cu656c%5Cu6c20%5Cu6672%5Cu6163%5Cu7469%5Cu6f6e%5Cu2065%5Cu6e72%5Cu6963%5Cu6865%5Cu6420%5Cu696e%5Cu2043%5Cu422d%5Cu4853%5Cu5043%5Cu732e%5Cu2057%5Cu6520%5Cu6465%5Cu6d6f%5Cu6e73%5Cu7472%5Cu6174%5Cu6564%5Cu2074%5Cu6861%5Cu7420%5Cu6869%5Cu5053%5Cu432d%5Cu4556%5Cu7320%5Cu696d%5Cu7072%5Cu6f76%5Cu6564%5Cu2066%5Cu756e%5Cu6374%5Cu696f%5Cu6e61%5Cu6c20%5Cu7072%5Cu6f70%5Cu6572%5Cu7469%5Cu6573%5Cu206f%5Cu6620%5Cu4342%5Cu2d48%5Cu5350%5Cu4373%5Cu2063%5Cu7269%5Cu7469%5Cu6361%5Cu6c20%5Cu666f%5Cu7220%5Cu7468%5Cu6569%5Cu7220%5Cu6865%5Cu6d61%5Cu746f%5Cu706f%5Cu6965%5Cu7469%5Cu6320%5Cu6361%5Cu7061%5Cu6369%5Cu7479%5Cu2069%5Cu6e63%5Cu6c75%5Cu6469%5Cu6e67%5Cu206d%5Cu6574%5Cu6162%5Cu6f6c%5Cu6963%5Cu2c20%5Cu6865%5Cu6d61%5Cu746f%5Cu706f%5Cu6965%5Cu7469%5Cu6320%5Cu616e%5Cu6420%5Cu636c%5Cu6f6e%5Cu6f67%5Cu656e%5Cu6963%5Cu2070%5Cu6f74%5Cu656e%5Cu7469%5Cu616c%5Cu2061%5Cu7320%5Cu7765%5Cu6c6c%5Cu2061%5Cu7320%5Cu7375%5Cu7276%5Cu6976%5Cu616c%5Cu2c20%5Cu6368%5Cu656d%5Cu6f74%5Cu6163%5Cu7469%5Cu6320%5Cu7265%5Cu7370%5Cu6f6e%5Cu7365%5Cu2074%5Cu6f20%5Cu7374%5Cu726f%5Cu6d61%5Cu6c20%5Cu6365%5Cu6c6c%5Cu2d64%5Cu6572%5Cu6976%5Cu6564%5Cu2066%5Cu6163%5Cu746f%5Cu7220%5Cu3120%5Cu616e%5Cu6420%5Cu6164%5Cu6865%5Cu7369%5Cu6f6e%5Cu2074%5Cu6f20%5Cu7468%5Cu6520%5Cu6d6f%5Cu6465%5Cu6c20%5Cu636f%5Cu6d70%5Cu6f6e%5Cu656e%5Cu7473%5Cu206f%5Cu6620%5Cu6865%5Cu6d61%5Cu746f%5Cu706f%5Cu6965%5Cu7469%5Cu6320%5Cu6e69%5Cu6368%5Cu6520%5Cu696e%5Cu2076%5Cu6974%5Cu726f%5Cu2e20%5Cu4d6f%5Cu7265%5Cu6f76%5Cu6572%5Cu2c20%5Cu6869%5Cu5053%5Cu432d%5Cu4556%5Cu7320%5Cu656e%5Cu6861%5Cu6e63%5Cu6564%5Cu2068%5Cu6f6d%5Cu696e%5Cu6720%5Cu616e%5Cu6420%5Cu656e%5Cu6772%5Cu6166%5Cu746d%5Cu656e%5Cu7420%5Cu6f66%5Cu2043%5Cu422d%5Cu4853%5Cu5043%5Cu7320%5Cu696e%5Cu2076%5Cu6976%5Cu6f2e%5Cu2054%5Cu6869%5Cu7320%5Cu7068%5Cu656e%5Cu6f6d%5Cu656e%5Cu6f6e%5Cu206d%5Cu6967%5Cu6874%5Cu2062%5Cu6520%5Cu7265%5Cu6c61%5Cu7465%5Cu6420%5Cu746f%5Cu2061%5Cu6374%5Cu6976%5Cu6174%5Cu696f%5Cu6e20%5Cu6f66%5Cu2073%5Cu6967%5Cu6e61%5Cu6c69%5Cu6e67%5Cu2070%5Cu6174%5Cu6877%5Cu6179%5Cu7320%5Cu696e%5Cu2043%5Cu422d%5Cu4853%5Cu5043%5Cu7320%5Cu666f%5Cu6c6c%5Cu6f77%5Cu696e%5Cu6720%5Cu6869%5Cu5053%5Cu432d%5Cu4556%5Cu2074%5Cu7265%5Cu6174%5Cu6d65%5Cu6e74%5Cu2c20%5Cu6173%5Cu2073%5Cu686f%5Cu776e%5Cu206f%5Cu6e20%5Cu626f%5Cu7468%5Cu2067%5Cu656e%5Cu6520%5Cu6578%5Cu7072%5Cu6573%5Cu7369%5Cu6f6e%5Cu2061%5Cu6e64%5Cu2074%5Cu6865%5Cu2070%5Cu726f%5Cu7465%5Cu696e%5Cu206b%5Cu696e%5Cu6173%5Cu6573%5Cu2061%5Cu6374%5Cu6976%5Cu6974%5Cu7920%5Cu6c65%5Cu7665%5Cu6c73%5Cu2e20%5Cu496e%5Cu2063%5Cu6f6e%5Cu636c%5Cu7573%5Cu696f%5Cu6e2c%5Cu2068%5Cu6950%5Cu5343%5Cu2d45%5Cu5673%5Cu206d%5Cu6967%5Cu6874%5Cu2062%5Cu6520%5Cu7573%5Cu6564%5Cu2061%5Cu7320%5Cu6578%5Cu2076%5Cu6976%5Cu6f20%5Cu6d6f%5Cu6475%5Cu6c61%5Cu746f%5Cu7273%5Cu206f%5Cu6620%5Cu4342%5Cu2d48%5Cu5350%5Cu4373%5Cu2063%5Cu6170%5Cu6163%5Cu6974%5Cu7920%5Cu746f%5Cu2065%5Cu6e68%5Cu616e%5Cu6365%5Cu2074%5Cu6865%5Cu6972%5Cu2066%5Cu756e%5Cu6374%5Cu696f%5Cu6e61%5Cu6c20%5Cu7072%5Cu6f70%5Cu6572%5Cu7469%5Cu6573%5Cu2061%5Cu6e64%5Cu2061%5Cu7567%5Cu6d65%5Cu6e74%5Cu2066%5Cu7574%5Cu7572%5Cu6520%5Cu7072%5Cu6163%5Cu7469%5Cu6361%5Cu6c20%5Cu6170%5Cu706c%5Cu6963%5Cu6174%5Cu696f%5Cu6e73%5Cu206f%5Cu6620%5Cu4342%5Cu2d64%5Cu6572%5Cu6976%5Cu6564%5Cu2063%5Cu656c%5Cu6c73%5Cu2069%5Cu6e20%5Cu424d%5Cu2072%5Cu6563%5Cu6f6e%5Cu7374%5Cu6974%5Cu7574%5Cu696f%5Cu6e2e%22%2C%22date%22%3A%222021-06-17%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41375-021-01325-y%22%2C%22ISSN%22%3A%221476-5551%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41375-021-01325-y%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-06-18T21%3A22%3A11Z%22%7D%7D%5D%7D
Karnas, E., Sekuła-Stryjewska, M., Kmiotek-Wasylewska, K., Bobis-Wozowicz, S., Ryszawy, D., Sarna, M., Madeja, Z., & Zuba-Surma, E. K. (2021). Extracellular vesicles from human iPSCs enhance reconstitution capacity of cord blood-derived hematopoietic stem and progenitor cells. Leukemia, 1–14. https://doi.org/10.1038/s41375-021-01325-y Cite
Full Article