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Pulmonary Cell NewsScientists demonstrated that hiPSC-extracellular vesicles improved functional properties of cord blood-HSPCs critical for their hematopoietic capacity including metabolic, hematopoietic and clonogenic potential as well as survival, chemotactic response to stromal cell-derived factor 1 and adhesion to the model components of hematopoietic niche in vitro.
[Leukemia]
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Karnas, E., Sekuła-Stryjewska, M., Kmiotek-Wasylewska, K., Bobis-Wozowicz, S., Ryszawy, D., Sarna, M., Madeja, Z., & Zuba-Surma, E. K. (2021). Extracellular vesicles from human iPSCs enhance reconstitution capacity of cord blood-derived hematopoietic stem and progenitor cells. Leukemia, 1–14. https://doi.org/10.1038/s41375-021-01325-y Cite
