B cells

[Nature Communications] Researchers showed that systemic delivery of αCD40 induced hypofunctional T cells and impaired the response to immune checkpoint inhibitors in pre-clinical glioma models.

[Human Genomics] Scientists used the commercial Chromium platform to perform sc-ATAC-seq to measure chromatin accessibility in 11,611 single umbilical cord blood cells derived from one trisomy 18 syndrome patient and one healthy donor.

[Nature Cancer] Scientists investigated the mechanisms of selection in childhood B-cell precursor acute lymphoblastic leukemia during induction chemotherapy where maximal cytoreduction occurs.

[Scientific Reports] An in-silico approach has been adopted to construct a multi-epitope vaccine from selected immunogenic extracellular vesicle proteins to elicit a cellular as well as a humoral immune response.

[Kite] Kite, a Gilead Company announced top-line results from the primary analysis of ZUMA-7, a randomized Phase III global, multicenter study showing superiority of Yescarta® compared to standard of care in second-line relapsed or refractory large B-cell lymphoma.

[Oncogene] Scientists summarized recent findings on the heterogeneous subset composition of B cells in both human and mouse tumor models and their different impacts on disease progression.