Inhibition of Kinesin Motor Protein KIFC1 by AZ82 Induces Multipolar Mitosis and Apoptosis in Prostate Cancer Cell

Scientists revealed that small KIFC1 inhibitor AZ82 suppresed the transcription and translation of KIFC1 significantly in PCa cells.
[Gene]
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Probucol Enhances the Therapeutic Efficiency of Mesenchymal Stem Cells in the Treatment of Erectile Dysfunction in Diabetic Rats by Prolonging their Survival Time via Nrf2 Pathway

The authors investigated therapeutic efficiency and potential mechanism of probucol combined with mesenchymal stem cells.
[Stem Cell Research & Therapy]
Wang, H., Zhang, K., Ruan, Z., Sun, D., Zhang, H., Lin, G., Hu, L., Zhao, S., & Fu, Q. (2020). Probucol enhances the therapeutic efficiency of mesenchymal stem cells in the treatment of erectile dysfunction in diabetic rats by prolonging their survival time via Nrf2 pathway. Stem Cell Research & Therapy, 11(1), 302. https://doi.org/10.1186/s13287-020-01788-3 Cite
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Antimalarial Agent Artesunate Induces G0/G1 Cell Cycle Arrest and Apoptosis via Increasing Intracellular ROS Levels in Normal Liver Cells

Researchers investigated the possible cytotoxic effects using normal BRL-3A and AML12 liver cells.
[Human & Experimental Toxicology]
Abstract

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