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Bax

Chlamydia trachomatis Inhibits Apoptosis in Infected Cells by Targeting the Pro-Apoptotic Proteins Bax and Bak

[Cell Death & Differentiation] Researchers provided a molecular analysis of chlamydial apoptosis-inhibition in infected human cells and demonstrate that the block of apoptosis occurs during the activation of the effectors of mitochondrial apoptosis, Bak and Bax.

Chlamydia trachomatis Inhibits Apoptosis in Infected Cells by Targeting the Pro-Apoptotic Proteins Bax and Bak

[Cell Death & Differentiation] Researchers provided a molecular analysis of chlamydial apoptosis-inhibition in infected human cells and demonstrate that the block of apoptosis occurs during the activation of the effectors of mitochondrial apoptosis, Bak and Bax.

Superoxide Anion Radical Induced Phototoxicity of 2,4, 5,6-Tetraminopyrimidine Sulfate via Mitochondrial-Mediated Apoptosis in Human Skin Keratinocytes at Ambient UVR Exposure

[Food and Chemical Toxicology] Researchers studied the photosensitization potential and mechanism involved in dermal phototoxicity of 2,4,5,6-tetraaminopyrimidine sulfate exposed to the dark and UVA/UVB/Sunlight by using different in-chemico and mammalian HaCaT cells, as test systems.

Gymnemic Acid Protects Murine Pancreatic β-Cells by Moderating Hyperglycemic Stress-Induced Inflammation and Apoptosis in Type 1 Diabetic Rats

[Journal of Biochemical and Molecular Toxicology] Scientists delineated the role of gymnemic acid in protecting pancreatic β-cells in diabetic animals, with special reference to inflammation and apoptosis.

Probiotics-Loaded Nanoparticles Attenuated Colon Inflammation, Oxidative Stress, and Apoptosis in Colitis

[Scientific Reports] Investigators explored the potential alleviating effects of dietary nano-supplement combined with bacillus strains in colitis a model.

LCZ696 Ameliorates Doxorubicin-Induced Cardiomyocyte Toxicity in Rats

[Scientific Reports] The authors investigated the potential benefit of LCZ696, an angiotensin receptor–neprilysin inhibitor against doxorubicin-induced cardiotoxicity in rats and H9c2 cells and determined whether the mechanism underlying any such effects involved its antioxidant activity.

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