Knocking down CREB-binding protein or Ku70 induced necrotic and paraptotic cell death as indicated by high-level intracellular reactive oxygen species, cytoplasmic vacuolization, and cell cycle arrest in the S phase.
[Cell Death Discovery]
Ding, L., Wen, Y., Zhang, X., Zhao, F., Lv, K., Shi, J., Shen, S., & Pan, X. (2021). Transcriptional network constituted of CBP, Ku70, NOX2, and BAX prevents the cell death of necrosis, paraptosis, and apoptosis in human melanoma. Cell Death Discovery, 7(1), 1–15. https://doi.org/10.1038/s41420-021-00417-z Cite
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