Tag results:

CD133

HN1L Promotes Stem Cell-Like Properties by Regulating TGF-β Signaling Pathway through Targeting FOXP2 in Prostate Cancer

[Cell Biology International] CD133+ cells were sorted from prostate cancer cells using magnetic fluorescence cell sorting technology and were considered as cancer stem cells.

MicroRNA-148a/152 Cluster Restrains Tumor Stem Cell Phenotype of Colon Cancer via Modulating CCT6A

[Anti-Cancer Drugs] Colon cancer stem cells were selected and high/low expression of miR-148a/152 plasmids were synthesized to intervene CD44+/CD133+ colon cancer stem cells to investigate the function of miR-148a/152 in invasion, migration, proliferation, colony formation and apoptosis of cells.

ADGRG1 Enriches for Functional Human Hematopoietic Stem Cells Following Ex Vivo Expansion-Induced Mitochondrial Oxidative Stress

[Journal of Clinical Investigation] Investigators reported that the frequencies of SCID repopulating cells were greatly decreased in cord blood CD34+ hematopoietic stem cells and hematopoietic progenitor cells upon ex vivo culture.

AKT Inhibitor AZD5363 Suppresses Stemness and Promotes Anti-Cancer Activity of 3,3′-Diindolylmethane in Human Breast Cancer Cells

[Toxicology and Applied Pharmacology] Investigators observed that proportion of CD133+Nanog+ subpopulation in MCF-7 cells was significantly increased after 3,3′-diindolylmethane administration with up-regulated AKT activity by using CyTOF assay.

Up-Regulation of miR-663a Inhibits the Cancer Stem Cell-Like Properties of Glioma via Repressing the KDM2A-Mediated TGF-β/SMAD Signaling Pathway

[Cell Cycle] Investigators explored the role and underlying mechanism of miR-663a in the proliferation, migration, invasion, and cancer stem cell-like properties of glioma cells.

Ethanol-Based Garlic Extract Prevents Malignant Evolution of Non-Invasive Breast Tumor Cells Induced by Moderate Hypoxia

[Biomedicine & Pharmacotherapy] Homemade ethanol-based garlic extract was administered to MCF7 and MCF10DCIS breast tumor cell lines grown under moderate hypoxia. Cell cycle, epithelial-to-mesenchymal transition and cancer stem cell markers were evaluated.

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