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Pulmonary Cell NewsInvestigators observed that proportion of CD133+Nanog+ subpopulation in MCF-7 cells was significantly increased after 3,3′-diindolylmethane administration with up-regulated AKT activity by using CyTOF assay.
[Toxicology and Applied Pharmacology]
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Zhu, K., Liu, X., Liu, C., Xu, Y., Fu, Y., Dong, W., Yan, Y., Wang, W., & Qian, C. (2021). AKT inhibitor AZD5363 suppresses stemness and promotes anti-cancer activity of 3,3′-diindolylmethane in human breast cancer cells. Toxicology and Applied Pharmacology, 429, 115700. https://doi.org/10.1016/j.taap.2021.115700 Cite
