CD8

[Hepatology] Hepatitis B virus infected HepG2-NTCP were treated with tenofovir disoproxil fumarate, Toll-like receptor 7/8 agonists, TLR7/8 conditioned media collected from immune cells, or RNAi using short-interfering RNAs.

[Blood] Investigators showed that concurrent ASXL1 and NRAS mutations defined a population of chronic myelomonocytic leukemia patients with shorter leukemia-free survival than those with ASXL1 mutation only.

[Cold Spring Harbor Perspectives in Biology] Scientists summarize the understanding of the current state in the human CD8+ T cell subset characterization field.

[Science Immunology] Researchers monitored T cell responses to the Spike protein of SARS-CoV-2 in 71 healthy donors vaccinated with two doses of the Pfizer–BioNTech mRNA vaccine for up to six months after vaccination.

[Cell Reports] Investigators analyzed over two million cells from 16 pancreata obtained from donors with type 2 diabetes and 13 pancreata from age-similar non-diabetic controls.

[Trends in Immunology] The authors review the progress in defining the key developmental and functional attributes of type 1 conventional dendritic cells (cDC1s) and the approaches to optimizing the potency of cDC1s for anticancer immunity.