CXCR3

[Cell Death & Disease] Researchers investigated the functional subsets of γδ T cells in hepatic fibrosis and to further explore the underlying causes and drivers of migration.

[Nature Immunology] Using a novel HLA-DRB1*15:01/S751 tetramer to track spike-specific CD4+ T cells, scientists showed that primary infection or vaccination induced robust S751-specific CXCR5− and cTFH cell memory responses.

[Modern Pathology] Ten patients had a history of B cell malignancies, one each of myeloid neoplasm, breast or prostate cancer, and four others had underlying immune disorders. Most patients died, mostly of disease, with a median overall survival of 12.7 months.

[Science Immunology] Scientists characterized tissue-resident memory B cells that were stably maintained in the lungs of mice after pulmonary influenza infection.

[Cell Reports] The authors observed distinct locations for parasite-specific T cell subsets, implying a link between differentiation and anatomical niches in the spleen.

[Immunological Reviews] The authors detail the inflammatory and chemokine regulators of spatially restricted T cell differentiation, with a focus on how to promote stem-like memory cell.