IL-6

[International Journal of Stem Cells] The protein expression of AKT, mTOR, p-AKT and p-mTOR was detected using western blot assay. The results showed that human umbilical cord mesenchymal stem cells treatment prominently promoted the glucocorticoid-induced the decrease of the collagen level and the increase of TRAP positive cells.

[Cancer Letters] Investigators showed that suboptimal T cell receptor stimulation of CD8+ T cells upregulated FOXP3 in vitro.

[Acta Biomaterialia] Scientists assessed the effects of sodium alginate microencapsulation on human MSC secretion of immunomodulatory cytokines in an osteoarthritis (OA) microenvironment and therapeutic efficacy in treating established OA.

[Scientific Reports] Scientists found that cytokine-specific autoantibodies (c-aAb) levels were stable over the course of hematopoietic stem cell transplantation, including at high titres, with few individuals seeming to acquire high-titre levels of c-aAbs.

[Journal of Experimental Medicine] The authors found that the STING S365A mutation, which abrogated IRF3 binding and type I interferon induction, rescued the embryonic lethality of DNase II−/− mice.

[Bioengineered] The underlying molecular mechanisms of PSP in improving insulin resistance (IR) in skeletal muscle remain unclear. PA induced an IR model in L6 myotubes. After treatment, cell proliferation was measured using the CCK8.