IL-6

[Scientific Reports] Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes from four healthy donors were incubated with lipopolysaccharides, TRPV1 agonist capsaicin or the antagonist capsazepine to investigate the role of transient receptor potential vanilloid 1 (TRPV1) for myocardial inflammation.

[Gene] After incubation of the HUVECs with HA of H1N1 for 24 hours, the mRNA and protein of ICAM-1 and IL-6 in HUVECs were increased in group of 5μg/ml concentration with statistical significance.

[Scientific Reports] Researchers investigated the effect of deleted in malignant brain tumors 1 (DMBT1) on doxorubicin-induced mucositis. Intestinal tissue was analyzed for the expression of DMBT1 and proinflammatory cytokines.

[Acta Pharmacologica Sinica] Diosmetin administration significantly decreased disease activity index score and ameliorated microscopic colon tissue damage, increased the expression of tight junction proteins, and reduced the secretion of proinflammatory cytokines IL-1β, IL-6, TNF-α, and Cox-2 in colon tissue.

[Stem Cell Research & Therapy] Scientists explored the effect and mechanism of glioma-associated MSCs on resistance to temozolomide in glioma cells.

[Phytotherapy Research] Scientists focused on the regulatory effects of parthenolide, a bioactive component derived from Chrysanthemum parthenium L., against hepatic fibrosis via regulating the crosstalk of toll-like receptor 4 and signal transducer and activator of transcription 3 in activated hepatic stellate cells.