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IL-6

Monocytic MDSCs Homing to Thymus Contribute to Age-Related CD8+ T Cell Tolerance of HBV

[Journal of Experimental Medicine] Investigators found that the frequency of hepatitis B surface antigen (HBsAg)-specific CD8+ T cells was inversely correlated with expansion of monocytic myeloid-derived suppressor cells in young rather than in adult chronic hepatitis B patients.

Ghrelin Pretreatment Enhanced the Protective Effect of Bone Marrow-Derived Mesenchymal Stem Cell-Conditioned Medium on Lipopolysaccharide-Induced Endothelial Cell Injury

[Molecular and Cellular Endocrinology] The authors investigated if ghrelin pretreatment enhanced the protective effect of bone marrow-derived mesenchymal stem cells-conditioned medium on lipopolysaccharide-induced endothelial cell injury.

LncRNA XIST Engages in Psoriasis via Sponging MiR-338-5p to Regulate Keratinocyte Proliferation and Inflammation

[Skin Pharmacology and Physiology] Scientists investigated the role and regulatory relationship between long noncoding RNA (lncRNA) XIST and miR-338-5p in psoriatic patients and cell models.

Safety and Efficacy of Autologous, Adipose-Derived Mesenchymal Stem Cells in Patients with Rheumatoid Arthritis: A Phase I/IIa, Open-Label, Non-Randomized Pilot Trial

[Stem Cell Research & Therapy] The authors performed a Phase I/IIa non-randomized, open-label study to evaluate the safety and efficacy of a single, intravenous infusion of autologous, adipose-derived MSCs over a period of 52 weeks, in patients with active rheumatoid arthritis.

MiR-146a Alleviates Lung Injury Caused by RSV Infection in Young Rats by Targeting TRAF-6 and Regulating JNK/ERKMAPK Signaling Pathways

[Scientific Reports] MiR-146a alleviated lung injury caused by respiratory syncytial virus (RSV) infection in young rats by targeting TRAF-6 and regulating JNK/ERK/MAPK signaling pathways.

Decidual Immune Response Following COVID-19 during Pregnancy Varies by Timing of Maternal SARS-CoV-2 Infection

[Journal of Reproductive Immunology] Investigators hypothesized that decidual leukocytes were altered by maternal SARS-CoV-2 infection in pregnancy and that this decidual immune response was shaped by the timing of infection during gestation.

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