MAPK

[Scientific Reports] Human CB-MSCs were isolated and characterized using flow cytometry. Cell differentiation has been induced by combining retinoic acid and sonic hedgehog in a two-step protocol for 14 days.

[Scientific Reports] Scientists explored miRNA profiles of CB-MSCs during differentiation into motor neuron-like cells.

[Cell Death Discovery] Scientists explored the ability of gastric cancer (GC) cell-derived extracellular vesicles (EVs)-mediated microRNA-129-5p/E2F transcription factor 7/mitogen-activated protein kinase/extracellular regulated protein kinase axis to affect the peritoneal metastasis of GC by delivering lncRNA small nucleolar RNA host gene 12.

[Cancer Gene Therapy] The authors investigated the differential regulatory effect of metabotropic glutamate receptor 5 on chemosensitivity in HCC and chemotoxicity to the normal liver.

[Cell Death Discovery] Researchers reported at the first time that JWA gene activating compound 1 (JAC1) inhibited the proliferation of TNBC in vitro and in vivo experimental models.

[Molecular Oncology] Targeting ubiquitin carboxyl-terminal hydrolase 28 (USP28) protein abundance at an early stage via inhibition of its activity is a feasible strategy for the treatment of early-stage lung tumors.