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Nestin

Nestin and NG2 Transgenes Reveal Two Populations of Perivascular Cells Stimulated by Photobiomodulation

[Journal of Cellular Physiology] The authors examined the early effect of photobiomodulation (PBM) in pericytes from experimentally injured pulp tissue. In vitro, PBM induced VEGF upregulation, improved dental pulp cells proliferation and migration, and favored their mineralization potential.

The Polarity Protein Par3 Coordinates Positively Self-Renewal and Negatively Invasiveness in Glioblastoma

[Cell Death & Disease] Researchers studied the role of the Par3 protein (encoded by PARD3) in glioblastoma multiforme (GBM). GBM patient transcriptomic data and patient-derived culture analysis indicated diverse levels of expression of PARD3 across and independent from subtypes

Schwann Cells Promote Prevascularization and Osteogenesis of Tissue-Engineered Bone via Bone Marrow Mesenchymal Stem Cell-Derived Endothelial Cells

[Stem Cell Research & Therapy] The authors cultured rat Schwann cells, aortic endothelial cells, and bone marrow-derived mesenchymal stem cells (BM-MSCs) and then obtained BM-MSC-derived induced endothelial cells and induced osteoblasts.

Matrigel Enhances Differentiation of Human Adipose Tissue-Derived Stem Cells Into Dopaminergic Neuron

[Neuroscience Letters] The authors investigated the differentiation capacity of human adult MSCs derived from adipose tissue into dopaminergic and neuron-like cells in the 3D culture plate.

Adult Neural Stem Cells Have Latent Inflammatory Potential That Is Kept Suppressed by Tcf4 to Facilitate Adult Neurogenesis

[Science Advances] we demonstrate that the adult hippocampal neural progenitors harbor an inflammatory potential that is proactively suppressed by transcription factor 4 (Tcf4).

Stem-Like Cells Drive NF1-Associated MPNST Functional Heterogeneity and Tumor Progression

[Cell Stem Cell] Investigators discovered and characterized a rare malignant peripheral nerve sheath tumor (MPNST) cell population with stem-cell-like properties, including quiescence, that was essential for tumor initiation and relapse.

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