PTEN

[Cell Death & Disease] Investigators studied the interaction between Notch receptors (Notch1-4) and PTEN, and demonstrated that Notch3 inhibited breast cancer proliferation and suppressed tumorigenesis by transactivating PTEN expression.

[Scientific Reports] Researchers measured a multidimensional migration phenotype for genetically defined human breast epithelial cell lines that ranged in their in vivo behavior from non-tumorigenic to aggressively metastatic.

[Nature Communications] Scientists provided evidence that the Activating Molecule in Beclin-1-Regulated Autophagy (Ambra1) contributed to melanoma development.

[Stem Cell Research & Therapy] Investigators elucidated the mechanism of sepsis-induced myocardial injury and examined the value of human umbilical cord mesenchymal stem cells (huMSCs) for protecting cardiac function in sepsis.

[Stem Cell Reviews and Reports] Researchers investigated the effects of extracellular vehicles secreted by human umbilical cord mesenchymal stem cells on angiogenesis under high glucose conditions in vivo and in vitro and to explore the underlying mechanisms.

[Journal of Pathology] Investigators report on efforts to generate patient‐derived organoids from a cohort of 81 prostate cancer specimens with diverse pathological and clinical features. They comprehensively analyzed histological features of each enrolled sample and correlated it with organoid growth patterns.