SHH

[Scientific Reports] Human CB-MSCs were isolated and characterized using flow cytometry. Cell differentiation has been induced by combining retinoic acid and sonic hedgehog in a two-step protocol for 14 days.

[Stem Cells and Development] Researchers established patient derived glioblastoma stem cells (GSCs), determined cancer stem cell marker expression, and immunostained GSCs to assess cell viability and apoptosis.

[Scientific Reports] Scientists explored miRNA profiles of CB-MSCs during differentiation into motor neuron-like cells.

[Scientific Reports] Researchers engineered cell sheets to develop a new in vitro model of ballooned hepatocytes.

[Cell Reports] Aneuploidy, defective differentiation, and inactivation of the tumor suppressor TP53 all occur frequently during tumorigenesis. Researchers probed the potential links among these cancer traits by inactivating TP53 in hESCs.

[Nature Communications] Scientists identified a mesenchymal-epithelial crosstalk that shapes the developing small intestine during late morphogenesis.