STAT3

[Scientific Reports] Researchers explored the roles and related mechanisms of lncRNA-TCONS_00147848 in nasal mucosa cell apoptosis and allergic rhinitis (AR). AR mice were sensitized with ovalbumin, with the TCONS_00147848 interference lentiviral vector and FOSL2 overexpressing lentiviral vectors constructed respectively.

[Cancer Letters] Investigators reported that the upregulated C-MET signaling acted as a compensatory mechanism that sustained the proliferation of chemoresistant cells in which EGFR family signaling was attenuated.

[Cell] Rhythmic segmented filamentous bacteria (SFB) attachment was driven by the circadian clock through control of feeding rhythms. Mechanistically, rhythmic SFB attachment activated an immunological circuit involving group 3 innate lymphoid cells.

[Cell Death & Disease] Scientists demonstrated that fibroblast growth factor-binding protein 1 was dramatically upregulated in airway epithelial cell lines treated by poly-L-arginine, a mimic of major basic protein.

[Oncology Reports] The authors highlight the latest research progress made in the biological functions and regulation of PIWI‑interacting RNA in mammals, their involvement in various cancer forms and their potential clinical applications.

[Cell Death & Disease] Researchers found that miR-526b-3p expression declined while programmed cell death protein ligand 1 (PD-L1) was elevated in cisplatin-resistant lung cancer compared to that in cisplatin-sensitive lung cancer by analyzing clinical samples.