T cells

[Blood Advances] Researchers examined whether serum levels of neurofilament light chain, a marker of neuroaxonal injury, correlated with the severity of immune effector cell-associated neurotoxicity syndrome.

[Cell Research] Researchers discovered a new STING agonist, CF501, and found that CF501-adjuvanted RBD-Fc vaccine elicited significantly stronger neutralizing antibody and T cell responses than Alum- and cGAMP-adjuvanted RBD-Fc in mice.

[BMC Medicine] Investigators compared the early immune responses against AZD1222 and BNT162b2. SARS-CoV-2 seronegative participants received a single dose of either vaccine and were analyzed for immune cell, effector T cell, and antibody dynamics.

[Journal of Leukocyte Biology] Aiming to develop an effective vaccine with rapid production, robust immunogenicity, and high protective efficiency, a DNA vaccine was designed by fusing influenza virus hemagglutinin (HA) with self-assembled ferritin nanoparticles, denoted as HA-F.

[Leukemia] To mitigate antigen escape and potentially improve the durability of remission, scientists developed a dual-targeting approach using an optimized, bispecific CAR construct that targets both CD19 and BAFF-R.

[Pediatric Research] Fetal B-1 and B-2 B cells involved in innate and adaptive immune responses, respectively, arise in staggered waves of development from distinct progenitors.