TGF-B

[Proceedings of the National Academy of Sciences of the United States of America] Tumor necrosis factor (TNF) deficiency did not affect viral load or leukocyte recruitment but caused severe lung pathology and excessive production of the cytokines interleukin (IL)-6, IL-10, transforming growth factor beta, and interferon gamma

[Cancer Discovery] Scientists showed that while WNT suppression blocked tumor growth in most organoid and in vivo colorectal cancer (CRC) models, the accumulation of CRC-associated genetic alterations enabled drug resistance and WNT-independent growth.

[Frontiers in Cell and Developmental Biology] The authors demonstrated that neuropilin (NRP)2 promoted Rac-1 mediated endothelial cell adhesion and migration over fibronectin matrices in a mechanistically distinct fashion to NRP1, showing no dependence on β3 integrin expression, or VEGF stimulation