TLR4

[Journal of Immunology Research] Using multiparametric flow cytometry, scientists identified mesenchymal, endothelial, and hematopoietic progenitor cells that express the secreted small protein Isthmin 1.

[Journal of innate Immunity] Extracellular vesicles released during acute lung injury originated from alveolar epithelial cells, macrophages, and neutrophils and carry a diverse array of lipid mediators derived from ω-3 and ω-6 polyunsaturated fatty acids.

[Nature Reviews Gastroenterology & Hepatology] The authors provide new evidence explaining the pathogenesis of necrotizing enterocolitis (NEC), explore new findings indicating that NEC development has origins before birth, and discuss future questions and opportunities for discovery in this field.

[Cell Death & Disease] Phenotypic and metabolic profiles with associated cellular signaling pathways involved in lipid metabolism were investigated in the mice heart and human cardiomyocytes to establish treatment effect of adiponectin's agonists.

[Cell Death Discovery] Scientists demonstrated that in the liver tissues and Kupffer cells of diabetes mellitus patients and streptozotocin-induced hyperglycemic mice, the endoplasmic reticulum stress-ATF6-CHOP signaling pathway was activated.

[Scientific Reports] The authors explored the anti-inflammatory effects and underlying molecular mechanism of povidone-iodine (PVP-I) on lipopolysaccharide-stimulated airway epithelial cells and investigated whether nasal instillation of PVP-I could suppress mucosal inflammation in non-eosinophilic chronic rhinosinusitis mice.