VEGF

[Oncogene] Liver-specific overexpression of GRB2-associated-binding protein 2 (Gab2) mice accelerated hepatoma progression possibly through activating IL-6-initiated the activation of myeloid-derived suppressor cells.

[Oncogene] Liver-specific overexpression of GRB2-associated-binding protein 2 (Gab2) mice accelerated hepatoma progression possibly through activating IL-6-initiated the activation of myeloid-derived suppressor cells.

[Molecular Cancer Research] Hypoxia increased androgen receptor expression and transcriptional activity in prostate cells in vitro.

[Cellular and Molecular Life Sciences] Researchers investigated the role of the endoplasmic reticulum-anchored protein, Protrudin, in endothelial cell protrusion, migration and angiogenesis.

[Scientific Reports] Scientists targeted Monoacylglycerol lipase (MAGL) in TNBCs, using a potent carbamate-based inhibitor AM9928 with prolonged pharmacodynamic effects. AM9928 blocked TNBC cell adhesion and transmigration across human brain microvascular endothelial cells in 3D co-cultures.

[Annals of Medicine] The authors comprehensively review the role of high-mobility group box 1 (HMGB1), hypoxia-inducible factor-1α (HIF-1α), and VEGF in doxorubicin-induced cardiovascular disease and its molecular mechanisms.