[Cell Death Discovery] IL-37 isoform D transgene amplified ST2+ immune cells, promoted M2 macrophage polarization and type 2 cytokine secretion in white adipose tissue that mediated beiging and inflammation resolution, thereby increasing energy expenditure, reducing obesity and insulin resistance in high-fat diet-fed mice.
[Cell Reports] Researchers reported a non-invasive all-optical strategy to induce stem cell differentiation in vitro and in vivo that activated individual target stem cells in situ by delivering a transient 100-ms irradiation of a tightly focused femtosecond laser to a submicron cytoplasmic region of primary adipose-derived stem cells.
[Ageless Biotech, Inc. (PR Newswire, Inc.)] Ageless Biotech, Inc. acquired a US FDA Investigational New Drug Application for the treatment of osteoarthritis of the knee, using minimally manipulated adipose derived stem cells without enzymes or other chemicals through a proprietary process of a well-known method referred to as stromal vascular fraction.
[Scientific Reports] The macroscopic view and histological sections revealed that the articular cartilage in the normal saline group was damaged, inflamed, uneven and thin, and had hyperchromatic cell infiltration.
[Current Stem Cell Research & Therapy] The authors explored the contribution of miRNAs in adipose-derived stem cell-extracellular vesicles to the treatment of cerebral ischemia.