asthma

[Allergy] Recently published articles and clinical trials are summarised and discussed with the goal to provide clinicians and researchers with a concise update on asthma research from a translational perspective.

[Nature Reviews Neurology] The authors focus on the emerging human evidence for an association between maternal immune activation and childhood neurodevelopmental disorders, including autism spectrum disorder, attention-deficit/hyperactivity disorder and Tourette syndrome.

[Cell Death & Disease] Scientists demonstrated that fibroblast growth factor-binding protein 1 was dramatically upregulated in airway epithelial cell lines treated by poly-L-arginine, a mimic of major basic protein.

[Scientific Reports] Primary human airway epithelial cells, cultured at air–liquid interface, were obtained by clinical airway brushings or from explanted lungs. Human airway Hb mRNA data were from publically available databases; or from RT-PCR.

[Environmental Toxicology] Investigators studied the possible role and mechanism of AMOTL2 in regulating transforming growth factor-β1 (TGF-β1)-induced proliferation and extracellular matrix (ECM) deposition of airway smooth muscle cells.

[Clinical & Translational Immunology] Researchers investigated cord blood immune cell populations from babies born to mothers with asthma in pregnancy.