astrocytes

[Neurology-Neuroimmunology & Neuroinflammation] Human CD8+ T lymphocytes from multiple sclerosis donors and age/sex-matched healthy controls were isolated to evaluate the functional impact of soluble ULBP4.

[Microbiome] Scientists used an integrated in vitro/in vivo approach to show that physiologically relevant concentrations of the dietary methylamine trimethylamine N-oxide enhanced blood-brain barrier integrity and protected it from inflammatory insult, acting through the tight junction regulator annexin A1.

[Scientific Reports] The authors investigated cellular injury-induced processes in the presence of amyloid β (Aβ) pathology and exposed a co-culture system of cortical stem-cell derived astrocytes, neurons and oligodendrocytes to Aβ42 protofibrils prior to a mechanically induced scratch injury.

[Nature Communications] Utilizing single-nuclei transcriptomics to characterize astrocytes after ischemic stroke in the visual cortex of the marmoset monkey, researchers observed nearly complete segregation between stroke and control astrocyte clusters.

[Neuron] To investigate neurogenic potential and cellular diversity, scientists profiled single-nucleus transcriptomes in five hippocampal-entorhinal subregions in humans, macaques, and pigs.

[Translational Psychiatry] Investigators used a human induced pluripotent stem cell (iPSC)-derived astrocyte model and investigated the temporal patterns of astroglia differentiation during developmental stages critical for schizophrenia using RNA sequencing.