basophils

[Experimental Hematology] Recent findings have shown the critical roles of signal-transducing adaptor protein (STAP)-2 in B cell progenitor cells in marrow under hematopoietic stress and STAP-1 and -2 in BCR-ABL-transduced leukemogenesis. In this review, the authors focus on the role of STAPs in the bone marrow.

[Journal of Experimental Medicine] Investigators developed new transgenic mice to profile pulmonary GM-CSF expression, which they detected in both immune cells, including group 2 innate lymphoid cells and γδ T cells, as well as AT2s.

[British Journal of Immunology] Investigators elucidated the function of short chain fatty acids on human basophils. Human basophils were purified from healthy donors by flow cytometric sorting.

[Cell Death & Disease] Cultured HrasG12S/+ keratinocytes exhibited increased IL-33 expression after Dermatophagoides farinae stimulation.

[Nature Medicine] Investigators identified a core peripheral blood immune signature across 63 hospital-treated patients with COVID-19 who were otherwise highly heterogeneous.