breast cancer cells

[Archives of Gynecology and Obstetrics] Researchers investigated the nuclear peroxisome proliferator-activated receptor gamma-dependent proliferation behavior of breast cancer cells after stimulation with matcha green tea extract.

[Experimental Hematology & Oncology] In vitro mammary spheroid formation, flow cytometry assay on CD24−/CD44+ sub-population, ALDH activity detection, cell viability assay and western blot analysis, and in vivo tumor-initiating analysis were performed to examine the effects of Tanshinone IIA on the stemness of breast cancer cells.

[Cell Death & Disease] Scientists found that the low expression of RICH1 in breast cancer was associated with poor prognosis. Depletion of RICH1 promoted the stemness and disrupted the normal epithelial architecture of MCF10A cells.

[Journal of Biomaterials Applications] Researchers demonstrated selective binding, effective uptake of herceptin (HER)-conjugated magnetic polystyrene-Agsbox nanoparticles into MDA-MB-231and SKBR-3 cell lines with no effect against L929.

[npj Breast Cancer] Scientists showed that reverting the high LIP/LAP ratios in TNBC cell lines into low LIP/LAP ratios by overexpression of LAP reduced migration and matrix invasion of these TNBC cells.

[Cell Reports] Investigators analyzed lineage-dependent gene expression in human breast tumors to identify differences in metabolic gene expression that may limit pathway redundancy and create therapeutic vulnerabilities.