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bronchial epithelial cells

Incense Smoke-Induced Oxidative Stress Disrupts Tight Junctions and Bronchial Epithelial Barrier Integrity and Induces Airway Hyperresponsiveness in Mouse Lungs

[Scientific Reports] Using mouse and cell culture models, the authors evaluated the effects of incense smoke exposure on airway hyperresponsiveness, expression of multiple epithelial tight junction- and adherens junction-associated mRNAs and proteins in the lungs, and the barrier function of bronchial epithelial cells assessed by transepithelial electronic resistance.

SARS-CoV-2 Variants Reveal Features Critical for Replication in Primary Human Cells

[PLOS Biology] By integrating viral sequencing data from patient material, virus stocks, and passaging experiments, together with kinetic virus replication data from nonhuman Vero-CCL81 cells and primary differentiated human bronchial epithelial cells (BEpCs), scientists observed several SARS-CoV-2 features that associated with distinct phenotypes.

Panaxydol Attenuates Ferroptosis against LPS-Induced Acute Lung Injury in Mice by Keap1-Nrf2/HO-1 Pathway

[Journal of Translational Medicine] In vivo, the role of panaxydol (PX) on lipopolysaccharide (LPS)-induced acute lung injury in mice was tested by determination of LPS-induced pulmonary inflammation, pulmonary edema and ferroptosis. In vitro, BEAS-2B cells were used to investigate the molecular mechanisms by which PX functions via determination of inflammation, ferroptosis and their relationship.

PGC-1α Regulates Airway Epithelial Barrier Dysfunction Induced by House Dust Mite

[Respiratory Research] BEAS-2B cells were exposed to house dust mite and the expressions of PGC-1α and E-cadherin were examined by immunoblotting.

Low-Dose Drosera rotundifolia Induces Gene Expression Changes in 16HBE Human Bronchial Epithelial Cells

[Scientific Reports] The biological functions of D. rotundifolia were explored in vitro following the treatment of bronchial epithelial cells, which are the potential targets of the pharmacological effects of the herbal medicine.

Outer Membrane Vesicles Derived from Klebsiella pneumoniae Influence the miRNA Expression Profile in Human Bronchial Epithelial BEAS-2B Cells

[Microorganisms] miRNA expression profiles in human bronchial epithelial cells were evaluated during infection with standard and clinical K. pneumoniae strains.

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