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bronchioalveolar stem cells

Multilineage Murine Stem Cells Generate Complex Organoids to Model Distal Lung Development and Disease

[EMBO Journal] The authors established a three‐dimensional murine bronchioalveolar lung organoid model that allows clonal expansion and self‐organization of FACS‐sorted bronchioalveolar stem cells upon co‐culture with lung‐resident mesenchymal cells.

Distal Lung Epithelial Progenitor Cell Function Declines with Age

[Scientific Reports] Investigators compared the lungs of 3- and 22-month old mice. They examined the gross morphological changes in these lungs, the density and function of epithelial progenitor populations and the epithelial gene expression profile.

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