Multilineage Murine Stem Cells Generate Complex Organoids to Model Distal Lung Development and Disease

By
Justin.choi
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0
59
The authors established a three‐dimensional murine bronchioalveolar lung organoid model that allows clonal expansion and self‐organization of FACS‐sorted bronchioalveolar stem cells upon co‐culture with lung‐resident mesenchymal cells.
[EMBO Journal]
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Vazquez-Armendariz, A. I., Heiner, M., El Agha, E., Salwig, I., Hoek, A., Hessler, M. C., Shalashova, I., Shrestha, A., Carraro, G., Mengel, J. P., Günther, A., Morty, R. E., Vadász, I., Schwemmle, M., Kummer, W., Hain, T., Goesmann, A., Bellusci, S., Seeger, W., … Herold, S. (2020). Multilineage murine stem cells generate complex organoids to model distal lung development and disease. The EMBO Journal, n/a(n/a), e103476. https://doi.org/10.15252/embj.2019103476 Cite
AbstractGraphical Abstract