Tag results:
cardiomyocytes
Muscle Cell News
Cardiac Fibroblasts Secrete Exosome microRNA to Suppress Cardiomyocyte Pyroptosis in Myocardial Ischemia/Reperfusion Injury
[Molecular and Cellular Biochemistry] Scientists showed that cardiac fibroblasts protected cardiomyocytes against myocardial ischemia/reperfusion-induced injury through suppression of pyroptosis.
Immune Regulation News
CCL17 Aggravates Myocardial Injury by Suppressing Recruitment of Regulatory T Cells
[Circulation] Investigators utilized mouse models of reperfused myocardial infarction, angiotensin II and phenylephrine infusion, and diphtheria toxin cardiomyocyte ablation to investigate C-C chemokine ligand 17.
ESC & iPSC News
Human iPSC Model Reveals a Central Role for NOX4 and Oxidative Stress in Duchenne Cardiomyopathy
[Stem Cell Reports] The authors used Duchenne muscular dystrophy-patient-specific human iPSCs to model cardiomyopathic features and unravel novel pathologic insights.
Cell Therapy News
In Vitro Matured Human Pluripotent Stem Cell-Derived Cardiomyocytes Form Grafts With Enhanced Structure and Function in Injured Hearts
[Circulation] The authors comprehensively phenotyped human PSC-cardiomyocytes after in vitro maturation for 20 and 40 days on either polydimethylsiloxaneor standard tissue culture plastic substrates.
Muscle Cell News
Generating 3D Human Cardiac Constructs from Pluripotent Stem Cells
[Ebiomedicine] Scientists discuss the advantages and limitations of 2D human pluripotent stem cell (hPSC)-cardiomyocyte system, and introduce the recent development of three-dimensional culture platforms derived from hPSCs.
Muscle Cell News
microRNA-124-3p Attenuates Myocardial Injury in Sepsis via Modulating SP1/HDAC4/HIF-1α Axis
[Cell Death Discovery] Septic rats were modeled by cecal ligation puncture while in vitro septic cardiomyocyte H9C2 were induced by lipopolysaccharide.