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caspase-3

Probiotics-Loaded Nanoparticles Attenuated Colon Inflammation, Oxidative Stress, and Apoptosis in Colitis

[Scientific Reports] Investigators explored the potential alleviating effects of dietary nano-supplement combined with bacillus strains in colitis a model.

Adipose Stem Cell-Derived Extracellular Vesicles Ameliorates Corticosterone-Induced Apoptosis in the Cortical Neurons via Inhibition of ER Stress

[Stem Cell Research & Therapy] To investigate neuroprotection effects of adipose stem cell-derived extracellular vesicles in the corticosterone (CORT)-induced cortical neurons, scientists cultured cortical neurons from E15 mice for 7 days, and the cultured cortical neurons were pretreated with different numbers for 30 min followed by administration of 200 μM CORT for 24 hours.

Hsp70 Overexpression in Drosophila Hemocytes Attenuates Benzene-Induced Immune and Developmental Toxicity via Regulating ROS/JNK Signaling Pathway

[Environmental Toxicology] Drosophila larvae exposed to benzene were examined for total hemocyte count, phagocytic activity, oxidative stress, apoptosis, and their developmental delay and reduction were analyzed.

Synergistic Combination of PMBA and 5-Fluorouracil (5-FU) in Targeting Mutant KRAS in 2D and 3D Colorectal Cancer Cells

[Heliyon] Scientists investigated the effect and efficacy of 2-pyridin-4-yl methylene β-boswellic acid (PMBA) and 5-FU in combination therapy compared in the treatment of KRAS mutant colon cancer.

HDAC11 Promotes Both NLRP3/Caspase-1/GSDMD and Caspase-3/GSDME Pathways Causing Pyroptosis via ERG in Vascular Endothelial Cells

[Cell Death Discovery] Researchers investigated the role of histone deacetylase 11 (HDAC11) in vascular endothelial cell pyroptosis and its molecular mechanism.

Knockdown of Circ_0001679 Alleviates Lipopolysaccharide-Induced MLE-12 Lung Cell Injury by Regulating the miR-338-3p/ Mitogen-Activated Protein Kinase 1 Axis

[Bioengineered] Researchers indicated that circ_0001679/miR-338-3p/MAPK1 axis may play an important role in the pathogenesis of acute lung injury.

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