celiac disease

[Scientific Reports] Gluten-specific T cells had a distinct transcriptional profile that mostly resembled that of Th1 cells but also expressed cytokines characteristic of other types of T-helper cells.

[Anokion SA] Anokion SA announced that the company has initiated patient dosing in the multiple ascending dose portion of its Assessment of KAN-101 in Celiac Disease disease, a Phase I clinical trial evaluating KAN-101 for the treatment of individuals with celiac disease.

[Mucosal Immunology] Scientists obtained γδ and αβ TCR sequences of >2500 single cells from blood and gut of 5 patients, before and during challenge. We observed extensive sharing between blood and gut γδ and CD8+ αβ T-cell clonotypes even prior to gluten challenge.

[Small] A cell‐free and anti‐inflammatory therapeutic system—probiomimetics—based on membrane vesicles of probiotic bacteria coupled to the surface of microparticles was developed.