cell culture

[Stem Cell Research & Therapy] Investigators compared the potential of human bone marrow MSCs cultured as 2D monolayers or 3D spheroids encapsulated in constructs of 3D-printed poly-L-lactide-co-trimethylene carbonate scaffolds and modified human platelet lysate hydrogels for bone regeneration.

[Science Advances] Researchers developed fibrous hydrogel assemblies that were stabilized with photocrosslinking and displayed fiber density–dependent strain-responsive properties.

[Polymer Journal] The authors used PNIPAAm-grafted substrates as a typical hydrophobic condensed polymer surface to investigate the effects of the lateral mobility of an adhesive ligand in the setting of lateral deformability of hydrophobic condensed polymer layers.

[Journal of Materials Chemistry B] The authors observed that prostate cancer cells and breast cancer cells cultured with nanodiamonds showed morphological changes and altered gene and protein expression.

[Microsystems & Nanoengineering] Investigators presented a simple strategy for using optical media discs with nanogrooves and other polymer-based substrates nanomolded from the discs to directly culture muscle cells to study their response to the effect of biophysical cues such as nanotopography and substrate stiffness.

[Tissue Engineering Part C-Methods] The authors described an effective method of isolating a human placenta substrate that induced the spontaneous formation of an interconnected network of green fluorescence labeled HUVECs in vitro.