cell culture

[Nature Medicine] Investigators evaluated the safety and activity of an antisense oligonucleotide targeting hepatitis B virus (HBV) RNA in both treatment-naïve and virally suppressed individuals with chronic HBV infection.

[Pancreas] Adopting a 3D rotary cell culture system, researchers co-cultured several PDAC cell lines and MIN6 islet β cells.

[Experimental Cell Research] Scientists discuss the patient-derived organoids as a native tumor microenvironment mimicking model in personalized cancer therapy.

[Oncology Reports] Researchers analyzed the effect of curcumol on prostate cancer and identify its possible internal regulatory pathway using in vitro cell culture and in vivo tumor model experiments.

[Stem Cell Reports] Isolated cells retain key in vivo self-renewal properties and their cell-type profile reflects the cell composition of their source area, while the function of the niche is sustained even eight months post-milking.

[Biomedicine & Pharmacotherapy] Scientists examined PMI-5011 activation of AMP-activated protein kinase (AMPK) signaling using murine C2C12 muscle cell culture and skeletal muscle tissue.