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cell culture

Differential Interferon-α Subtype Induced Immune Signatures Are Associated with Suppression of SARS-CoV-2 Infection

[Proceedings of the National Academy of Sciences of the United States of America] Investigators comprehensively analyzed the antiviral activity of all IFNα subtypes against SARS-CoV-2 to identify the underlying immune signatures and explore their therapeutic potential.

Lactate Maintains BCR/Abl Expression and Signaling in Chronic Myeloid Leukemia Cells under Nutrient Restriction

[Oncology Research] Investigators directed a study to deepen the effects of nutrient shortage on BCR/Ablprotein expression and signaling in chronic myeloid leukemia cells.

RNA-Seq of Nine Canine Prostate Cancer Cell Lines Reveals Diverse Therapeutic Target Signatures

[Cancer Cell International] Investigators compared the transcriptomes of nine canine cell lines derived from prostate adenocarcinoma (PAC), PAC metastasis and transitional cell carcinoma to their respective original primary tumor or metastasis tissues.

NorthSea Therapeutics Initiates Phase 1 Trial of SEFA-6179, Targeting the Orphan Indication Intestinal Failure-Associated Liver Disease

[NorthSea Therapeutics B.V.] NorthSea Therapeutics B.V. announced it has initiated a Phase I study with SEFA-6179 in adult subjects, targeting the initial orphan indication of the treatment of intestinal failure associated liver disease.

Accelerated Embryonic Stem Cell Screening with a Highly Efficient Genotyping Pipeline

[Molecular Biology Reports] Scientists optimized and functionally linked magnetic activated cell sorting technology as well as multiplex droplet digital PCR to their ESC screening process to achieve a greater than 60% assurance that ESC clones were correctly targeted.

Treatment of Kidney Clear Cell Carcinoma, Lung Adenocarcinoma and Glioblastoma Cell Lines with Hydrogels Made of DNA Nanostars

[Biomaterials Science] Investigators studied the biological response of three different cell lines to the treatment with DNA-GEL – a DNA-based hydrogel composed of interacting DNA nanostars.

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