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cell culture

A20 (TNFAIP3) Alleviates Viral Myocarditis through ADAR1/miR-1a-3p-Dependent Regulation

[BMC Cardiovascular Disorders] A20 was underexpressed and miR-1a-3p was overexpressed in the myocardium of VMC mice as well as in Coxsackie virus B3-infected cardiomyocytes.

LncRNA MEG3 Ameliorates NiO Nanoparticles-Induced Pulmonary Inflammatory Damage via Suppressing the p38 Mitogen Activated Protein Kinases Pathway

[Environmental Toxicology] Wistar rats were treated with nickel oxide nanoparticles (NiO NPs) suspensions by intratracheal instillation twice-weekly for nine weeks. A549 cells were treated with NiO NPs suspensions for 24 hour.

Placental Mammals Acquired Functional Sequences in NRK for Regulating the CK2-PTEN-AKT Pathway and Placental Cell Proliferation

[Molecular Biology and Evolution] Scientists showed the molecular evolution of NCK-interacting kinase-related kinase, which confered its function for inhibiting placental cell proliferation.

Lung Epithelial Cells Interact with Immune Cells and Bacteria to Shape the Microenvironment in Tuberculosis

[Thorax] Scientists discuss the interplay between lung endothelial cell, immune cells and Mycobacterium tuberculosis (Mtb) and argue that modeling these interactions is of key importance to unravel early events during Mtb infection.

3D Hanging Spheroid Plate for High-Throughput CAR T Cell Cytotoxicity Assay

[Journal of Nanobiotechnology] Scientists presented a 3D hanging spheroid plate, which facilitated the formation of spheroids and the separation of unbound and dead cells from spheroids during cytotoxicity assays.

Engineering Brain Assembloids to Interrogate Human Neural Circuits

[Nature Protocols] Scientists presented how to generate 3D spheroids resembling specific domains of the nervous system and then how to integrate them physically to allow axonal projections and synaptic assembly.

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