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cell proliferation

COL11A1 Activates Cancer-Associated Fibroblasts by Modulating TGF-β3 through the NF-κB/IGFBP2 Axis in Ovarian Cancer Cells

[Oncogene] Collagen type XI alpha 1 (COL11A1) is overexpressed in cancer-associated fibroblasts (CAFs); therefore this study examined its role during CAF activation in epithelial ovarian cancer.

Signaling Pathways in Cancer-Associated Fibroblasts and Targeted Therapy for Cancer

[Signal Transduction and Targeted Therapy] Scientists summarize the enormous amounts of findings on the signals mediating crosstalk of cancer-associated fibroblasts with cancer cells and its related targets or trials.

miR-802 Regulates Paneth Cell Function and Enterocyte Differentiation in the Mouse Small Intestine

[Nature Communications] Investigators showed that the intestine-enriched miR-802 was a central regulator of intestinal epithelial cell proliferation, Paneth cell function, and enterocyte differentiation.

LncRNA Bmp1 Promotes the Healing of Intestinal Mucosal Lesions via the miR-128-3p/PHF6/PI3K/AKT Pathway

[Cell Death & Disease] The authors investigated the mechanisms of action of long non-coding RNA Bmp1 on damaged intestinal mucosa. They found that Bmp1 was increased in damaged intestinal mucosal tissue and Bmp1 overexpression was able to alleviate intestinal mucosal injury.

Long Noncoding RNAs in Triple-Negative Breast Cancer: A New Frontier in the Regulation of Tumorigenesis

[Journal of Cellular Physiology] The authors highlight the association of several long noncoding RNAs in TNBC progression and treatment, along with their possible functions and mechanisms.

Inhibition of miR-1298-5p Attenuates Sepsis Lung Injury by Targeting SOCS6

[Molecular and Cellular Biochemistry] miR-1298-5p and suppressor of cytokine signaling 6 (SOCS6) were silenced or overexpressed in human bronchial epithelial cells. PKH-67 Dye was used to trace exosome endocytosis.

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