cell proliferation

[Cell Death & Disease] Scientists demonstrated that autophagy-associated circular RNAs (circRNA) circ-autophagy related 7 (circATG7) was elevated in pancreatic cancer (PC) tissues compared to adjacent tissues.

[Frontiers in Oncology] Investigators revealed that PLA2G6 was up-regulated in cutaneous malignant melanoma tissues compared to nevus tissues, as well as increased in vitro in SK-MEL-28 and M14 melanoma cell lines compared to human melanocytes.

[Clinical Rheumatology] Scientists investigated the structural and functional changes in the localized scleroderma (LSc) epidermis and further explored the underlying mechanisms, providing a new angle to treat LSc in the clinic.

[Melanoma Research] LINC01063 knockdown impeded melanoma cell proliferation, migration, invasion, and epithelial-mesenchymal transition as well as melanoma tumor growth.

[Cell Reports] Scientists reported that tumor-derived Jagged1 is a key regulator of the tumor immune microenvironment. Jagged1 promoted tumorigenesis in multiple spontaneous mammary tumor models.

[Science Signaling] In human pulmonary aortic endothelial cells,lipopolysaccharide (LPS) induced decreased in the amounts of endothelial nitric oxide synthase, thrombomodulin, and vascular endothelial–cadherin, which was blocked by treatment with UNC2250.