The Suppressive Effects of Mer Inhibition on Inflammatory Responses in the Pathogenesis of LPS-Induced ALI/ARDS

In human pulmonary aortic endothelial cells,lipopolysaccharide (LPS) induced decreased in the amounts of endothelial nitric oxide synthase, thrombomodulin, and vascular endothelial–cadherin, which was blocked by treatment with UNC2250.